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Bodybuilding is een veeleisende sport die niet alleen dedication en discipline vereist, maar ook een diepgaand begrip van trainingstechnieken en voeding. In de wereld van bodybuilding zijn bepaalde hulpmiddelen in opkomst gekomen die door veel atleten worden gebruikt om hun prestaties te verbeteren. Een van de meest besproken en controversiële van deze hulpmiddelen zijn steroïden.
https://devacute.com/de-rol-van-steroiden-bij-het-optimaliseren-van-bodybuildingprestaties/
Steroïden zijn kunstmatig geproduceerde varianten van het mannelijke geslachtshormoon testosteron. Ze worden vaak gebruikt om spiergroei en kracht te bevorderen. Er zijn verschillende soorten steroïden, enkele van de meest voorkomende zijn:
Steroïden werken door zich te binden aan de androgenreceptoren in de spieren, wat leidt tot een verhoogde eiwitsynthese en spiergroei. Dit proces heeft verschillende effecten op het lichaam:
Hoewel steroïden aanzienlijke voordelen kunnen bieden voor bodybuilders, zijn er ook vele risico’s en bijwerkingen aan verbonden. Deze kunnen omvatten:
De rol van steroïden in bodybuilding is complex en vol tegenstrijdigheden. Terwijl ze aanzienlijke voordelen kunnen bieden bij het optimaliseren van prestaties, gaat dit vaak gepaard met ernstige gezondheidsrisico’s. Bodybuilders moeten goed geïnformeerd zijn over de gevolgen van het gebruik van steroïden en overwegen om alternatieve methoden voor prestatieverbetering, zoals voedingssupplementen en trainingsprogramma’s, te gebruiken.
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The Air Jordan 4 claims a distinct spot in sneaker culture — it’s the model that established Michael Jordan’s authority both on the basketball court and in the retail world. Conceived by the celebrated Tinker Hatfield and first introduced in 1989, the AJ4 featured exposed Air units, molded wing eyelets, and a mesh ventilation system that was revolutionary for its time. Fast forward to 2026, and the Jordan 4 stays one of the most wanted designs in the full sneaker industry, with MSRP beginning around $210 and resale values that can climb well into four-figure territory for restricted runs. Whether you’re a first-time buyer or a seasoned collector, this resource examines everything you need to know before opening your wallet. We’ll cover the different versions, authentication tips, fit recommendations, and which 2026 launches merit your focus.
The Air Jordan 4 debuted on February 22, 1989, and right away turned into a cultural landmark extending far beyond basketball arenas. It was the first Jordan sneaker to achieve a international drop, widening Nike’s footprint into markets worldwide and producing an reported $100 million in revenue during its opening year. Tinker Hatfield derived ideas from utilitarian and military styling, adding visible support structures and functional details that delivered the shoe an striking, mechanical look. The AJ4 gained Hollywood fame when Spike Lee showcased it in the 1989 movie “Do the Right Thing,” with the character Buggin’ Out triggering a conflict over a stepped-on pair. Michael Jordan himself sported the sneaker during his famous “The Shot” against Cleveland in the 1989 Playoffs — a floating, double-clutch game-winner over Craig Ehlo that endures as one of basketball’s most rewatched plays. This crossroads of on-court excellence, Hollywood, and streetwear culture elevated the Jordan 4 from a basketball sneaker to a real cultural icon that still manages to command recognition 37 years later.
Not all Jordan 4s are built alike, and understanding the nuances helps you avoid wasting hard-earned dollars and possible regret. The Air Jordan 4 Retro OG is the flagship tier, featuring materials that accurately mirror the debut 1989 edition at $210-$225. The Retro SE (Special Edition) offers special construction materials like canvas, patent leather, or luxury suede, priced between $200-$250. The Jordan 4 RM (Reimagined) applies innovative choices with the silhouette, at times reworking the sole or including unexpected materials. Jordan Brand also produces Golf and Lifestyle versions that adapt the outsole for dedicated purposes. Women’s dedicated colorways have risen markedly, with specific sizing that regularly is snapped up faster than men’s drops.
| Jordan 4 Version | Retail Price (2026) | Build Materials | Recommended For |
|---|---|---|---|
| Retro OG | $210–$225 | OG-spec leather/nubuck | Collectors, purists |
| Retro SE | $200–$250 | Canvas, patent, premium suede | Fashion enthusiasts |
| Reimagined (RM) | $215–$260 | Experimental blends | Trendsetters |
| Golf Edition | $220–$240 | Waterproof leather, spiked sole | Golfers |
| Women’s Exclusive | $200–$230 | Changes per edition | Unique colorways |
Selecting the right size in Jordan 4s is essential because the shoe has a unique fit than many other kicks, and exchanges on limited releases can be extremely difficult. Typically, the Jordan 4 fits true to size for those with medium-width feet. However, if you have wide feet, choosing a half size larger is definitely recommended because the midfoot cage and wing eyelets create a tight lockdown that will not give over time. The forefoot area is slightly snug compared to sneakers like the Air Force 1. Breaking in is average — count on about a week of steady wear before the materials relax. When trying them on in a shop, put on the socks you plan to wear regularly, as sock density can mean the distinction between a comfortable fit and painful pressure points.
The counterfeit industry has become alarmingly advanced, and the Jordan 4 is one of the most counterfeited sneakers, turning verification a must. Start with the box: legitimate shoes have precise print work, even fonts, and a matching size label on both the packaging and inner tag. The midsole coating should be sharp with no running, and the visible Air unit should be centered and clear of air bubbles. Check the “Flight” tongue text — genuine stitching is clean and regularly spaced, while counterfeits exhibit sloppy threads or erratic spacing. The outsole’s herringbone pattern should be cleanly cut with regular depth. For transactions above retail price, turn to verification services from eBay’s Authenticity Guarantee, GOAT, or CheckCheck — the $10-15 cost is minor compared to the cost of a knockoff pair.
The 2026 Jordan 4 drop schedule is brimming with much-hyped releases. Early in the year, Jordan Brand released the AJ4 “Oxidized Green,” offering high-quality suede with aged-look midsoles that were depleted within moments on SNKRS. The springtime lineup contains the eagerly awaited “Bred Reimagined,” adding cracked leather and aged touches to the classic black and red color combination. Summer features a fresh A Ma Maniére collab, known for high-end collaborations that pull premium aftermarket values. For cost-aware shoppers, standard colorways in the $210 range are anticipated throughout the fall. Jordan Brand has also unveiled a green AJ4 featuring at least 20% reclaimed fabrics, furthering Nike’s Move to Zero campaign. Stay updated through the Nike SNKRS app to boost your chances of landing pairs at MSRP.
Knowing where to shop is every bit as essential as understanding what to purchase, and the world of sneaker shopping continues to shift in 2026. The Nike SNKRS app persists as the primary platform for exclusive launches, running a draw system that provides every applicant an equal chance — though scoring still feels like hitting the lottery with some drops drawing over 500,000 submissions. Official outlets like Foot Locker, Finish Line, and JD Sports receive supply, and registering for their membership programs and release notifications provides you with a measurable boost in copping pairs. For resale purchases, reputable marketplaces like StockX, GOAT, and eBay with Authenticity Guarantee supply purchase protection and verification services that considerably reduce the risk of ending up with fake products. Community resale boutiques and sneaker meets are great for uncovering discounts on pre-owned sneakers and examining pairs in person before handing over your funds. Stay away from shopping with unchecked accounts on social media platforms or classified ads, where the rate of knockoff products exceeds 30% according to industry data. Cross-referencing prices across multiple platforms before purchasing can net you savings of anywhere from $20 to $100 on the same pair, so doing your homework saves real money.
Safeguarding your Jordan 4 investment demands correct maintenance, above all in light of retail prices of $200 or more. Scrub after every few wears by applying a soft brush, warm water, and sneaker cleaner — skip domestic cleaners that fade colors. Nubuck and suede panels are at risk of water stains, so spray on water-resistant spray before the first outing. House in a dry and cool environment away from UV light, as UV triggers discoloration on white midsoles within months. Shoe trees hold shape, and silica gel packets combat humidity for long-term storage. If you’re getting your first pair, a GR OG edition in a neutral color provides the real vibe without limited-edition stress. Collectors should set price alerts on several aftermarket platforms and respond swiftly when costs decrease. The Jordan 4 possesses both cultural weight and investment potential, rendering it one of the wisest shoe purchases in 2026.
For the latest drop dates, check out the main Jordan Brand page on Nike.com.
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Hippocratic AI raises $141M to staff hospitals with clinical AI agents
Meanwhile, Kristina Dulaney, RN, PMH-C, the founder of Cherished Mom, an organization dedicated to solving maternal mental health challenges, helped to create an AI agent that’s focused on helping new mothers navigate such problems with postpartum mental health assessments and depression screening. The startup was initially focused on creating generative AI chatbots to support clinicians and other healthcare professionals, but has since switched its focus to patients themselves. Its most advanced models take advantage of the latest developments in AI agents, which are a form of AI that can perform more complex tasks while working unsupervised. Despite rapid advancements in AI, creators in open-source ecosystems face significant challenges in monetizing derivative works and securing proper attribution.
Story, the global intellectual property blockchain, has announced its integration with Stability AI’s state-of-the-art models to revolutionize open-source AI development. This collaboration enables creators, developers, and artists to capture the value they contribute to the AI ecosystem by leveraging blockchain technology to ensure proper attribution, tracking, and monetization of creative works generated through AI. Andreessen Horowitz, or a16z, is investing in AI and biotech to lead the way in innovation.
In a statement, Raspberry AI said the funding would be used to accelerate its product development and add top engineering, sales and marketing talent to its team. But with U.S. companies raising and/or spending record sums on new AI infrastructure that many experts have noted depreciate rapidly (due to hardware/chip and software advancements), the question remains which vision of the future will win out in the end to become the dominant AI provider for the world. Or maybe it will always be a multiplicity of models each with a smaller market share? That’s followed by more extensive evaluations and safety assessments by an extensive network of more than 6,000 nurses and 300 doctors, who will confirm that it passes all required safety tests.
Once the AI agent is up and running, the clinicians who created it will be able to claim a share of the revenue it generates from the startup’s customers. Currently the technology is being used by Under Armour, MCM Worldwide, Gruppo Teddy and Li & Fung to create and iterate apparel, footwear and accessories styles. The company’s existing investors Greycroft, Correlation Ventures and MVP Ventures also joined in the round, along with notable angel investors, including Gokul Rajaram and Ken Pilot. Clearly, even as he espouses a commitment to open source AI, Zuck is not convinced that DeepSeek’s approach of optimizing for efficiency while leveraging far fewer GPUs than major labs is the right one for Meta, or for the future of AI.
Story is the world’s intellectual property blockchain, transforming IP into networks that transcend mediums and platforms, unleashing global creativity and liquidity. By integrating Stability AI’s advanced models, Story is taking a significant step toward building a fair and sustainable internet for creators and developers in the age of generative AI. Hippocratic AI said it’s necessary to have clinicians onboard because they have, over the course of their careers, developed deep expertise in their respective fields, as well as the practical insights to help cure specific medical conditions and the clinical workflows involved.
Investing in Raspberry AI.
Posted: Mon, 13 Jan 2025 08:00:00 GMT [source]
Story aims to bridge this gap by combining Stability AI’s cutting-edge technology with blockchain’s ability to secure digital property rights. For example, creators could register unique styles or voices as intellectual property on Story with transparent usage terms. This would enable others to train and fine-tune AI models using this IP, ensuring that all contributors in the creative chain benefit when outputs are monetized.
Holger Mueller of Constellation Research Inc. said Hippocratic AI is bringing two of the leading technology trends to the healthcare industry, namely no-code or low-code software development and AI agents. The launch is a bold step forward in healthcare innovation, giving clinicians the opportunity to participate in the design of AI agents that can address various aspects of patient care. It says clinicians can create an AI agent prototype that specializes in their area of focus in less than 30 minutes, and around three to four hours to develop one that can be tested. Shah said the last nine months since the company’s previous $50 million funding round have seen it make tremendous progress. During that time, it has received its first U.S. patents, fully evaluated and verified the safety of its first AI healthcare agents, and signed contracts with 23 health systems, payers and pharma clients.
For instance, one of its AI agents is specialized in chronic care management, medication checks and post-discharge follow-up regarding specific conditions such as kidney failure and congestive heart failure. The healthcare-focused artificial intelligence startup Hippocratic AI Inc. said today it has closed on a $141 million Series B funding round that brings its total amount raised to more than $278 million. “This round of financing will accelerate the development and deployment of the Hippocratic generative AI-driven super staffing and continue our quest to make healthcare abundance a reality,” he promised. Raspberry AI, the generative AI platform for fashion creatives, has secured 24 million US dollars in Series A funding led by Andreessen Horowitz (a16z). Today, we’re going in-depth on blockchain innovation with Robert Roose, an entrepreneur who’s on a mission to fix today’s broken monetary system. Hippocratic AI’s early customers include Arkos Health Inc., Belong Health Inc., Cincinnati Children’s, Fraser Health Authority (Canada), GuideHealth, Honor Health, Deca Dental Management, LLC, OhioHealth, WellSpan Health and other well-known healthcare systems and hospitals.
By incorporating this wisdom into its AI agents, it’s making them safer and improving patient outcomes, it said. Crucially, any agent created using its platform will undergo extensive safety training by both the creator and Hippocratic AI’s own staff. Every clinician will have access to a dashboard to track their AI agent’s performance and use and receive feedback for further development.
All these indicate the commitment a16z has in shaping the future of technology and healthcare through strategic investments. Both platforms use Stability AI’s models to bring creators’ visions to life and Story’s blockchain technology to enable provenance and attribution throughout the creative process. These real-world applications highlight how creators can safeguard their intellectual property while thriving in a shared creative economy. Raspberry AI offers brands and manufacturing creative teams technology solutions, which can help accelerate each stage of the fashion product development cycle to increase speed to market and profitability while reducing costs. Andreessen Horowitz, or a16z, is one of the leading AI investors and targets only innovative startups. They participated in the round that funded Anysphere on January 14, 2025, with a total sum of $105 million for an AI coding tool known as Cursor, whose valuation has reached $2.5 billion.
In order to ensure its AI agents can do their jobs safely, Hippocratic AI says it only works with licensed clinicians to develop them, taking steps to verify their qualifications and experience first. Once clinicians have built their agents, they’ll be submitted to the startup for an initial round of testing. Through the Hippocratic AI Agent App Store, healthcare organizations and hospitals will be able to access a range of specialized AI agents for different aspects of medical care.
The startup was co-founded by Chief Executive Officer and serial entrepreneur Munjal Shah and a group of physicians, hospital administrators, healthcare professionals and AI researchers from organizations including El Camino Health LLC, Johns Hopkins University, Stanford University, Microsoft Corp., Google and Nvidia Corp. PIP Labs, an initial core contributor to the Story Network, is backed by investors including a16z crypto, Endeavor, and Polychain. Co-founded by a serial entrepreneur with a $440M exit and DeepMind’s youngest PM, PIP Labs boasts a veteran founding executive team with expertise in consumer tech, generative AI, and Web3 infrastructure. The startup has also created other AI agents for tasks like pre- and post-surgery wound care, extreme heat wave preparation, home health checks, diabetes screening and education, and many more besides. The startup said its AI Agent creators include Dr. Vanessa Dorismond MD, MA, MAS, a distinguished obstetrician and gynecologist at El Camino Women’s Medical Group and Teal Health, who helped to create an AI agent that’s focused on cervical cancer check-ins and enhancing patient education. According to the startup, the objective of these AI agents is to try and solve the massive shortage of trained nurses, social workers and nutritionists in the healthcare industry, both in the U.S. and globally.
The same day, a16z also led a Series A investment in Slingshot AI, which has raised a total of $40 million to create a foundation model for psychology. Those investments highlight the commitment of the group to using AI to address important issues and are also focusing on how AI can improve different industries, including healthcare and consumer services. In general, a16z is committed to supporting AI innovations that could have a profound impact on society. We are thrilled to see our models used in Story’s blockchain technology to ensure proper attribution and reward contributors,” said Scott Trowbridge, Vice President of Stability AI. Others include Kacie Spencer, DNP, RN, the chief nursing officer at Adtalem Global Education Inc., who has more than 20 years of experience in emergency nursing and clinical education. Her AI agent is focused on patient education for the proper installation of child car seats.
It participated in an Anysphere round that had the company raising $105 million on January 14, 2025, when it pushed the valuation up to $2.5 billion. Beyond this, it has also released a $500 million Biotech Ecosystem Venture Fund with Eli Lilly to place a focus on health technologies, but with the aspect of innovative applications. On the same day, they led a Series A investment in Slingshot AI, a company that’s developing advanced generative AI technology for mental health. Additionally, a16z invested in Raspberry AI to bring generative AI to the front of fashion design and production. In December 2024, they envisioned a future in which AI was used aggressively in nearly all sectors.
